By William W. Cohen
This useful consultant offers a succinct therapy of the overall thoughts of cellphone biology, furnishing the pc scientist with the instruments essential to learn and comprehend present literature within the field.
The e-book explores 3 assorted elements of biology: biological structures, experimental methods, and language and nomenclature. After a quick creation to telephone biology, the textual content makes a speciality of the rules at the back of the most-widely used experimental tactics and mechanisms, referring to them to well-understood innovations in laptop technology.
The presentation of the cloth has been ready for the reader’s speedy seize of the subject: reviews on nomenclature and historical past notes might be ascertained at a look, and crucial vocabulary is boldfaced through the textual content for simple identification.
Computer technology researchers, pros and desktop technological know-how scholars will locate this an incomparable source and a very good start line for a extra accomplished exam of phone biology.
"This concise booklet is a superb advent for machine scientists to the interesting revolution less than method in molecular biology. It presents lucid, high-level descriptions of the basic molecular mechanisms of lifestyles, and discusses the computational rules concerned. I want this little gem used to be to be had whilst i used to be ‘learning the ropes’– it can were my first selection of interpreting material."
--Roni Rosenfeld, Carnegie Mellon University
Read Online or Download A Computer Scientist's Guide to Cell Biology: A travelogue from a stranger in a strange land PDF
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Additional resources for A Computer Scientist's Guide to Cell Biology: A travelogue from a stranger in a strange land
Genes expressed in neither A nor B 52 A Computer Scientist’s Guide to Cell Biology will have black locations. Genes expressed by A and not B will show as green, and genes expressed by B and not A will be red. The intensity of a color indicates the level of expression—that is, the number of mRNA molecules being transcribed. A gene chip has a similar function, but different construction. ) right on the chip. Often the sequences are chosen so that there is a known, unambiguous mapping between these sequences and genes from some sequenced genome; in this case, gene chips can be used in the same manner as a microarray.
Cohen 35 materials from organelle to organelle; and within the cytoplasm, some proteins are hauled from place to place along microtubules, which are long fibers that run radially from the center of the cell to the periphery. Transport in eukaryotic cells leads to locality, and hence to some degree of modularity, which can be used to help understand cellular processes. More generally, the subcellular location at which proteins are found is often an important indicator of function. It should also be emphasized that, while membranes provide some notion of locality inside a cell, membranes allow small molecules to diffuse through them, and biological membranes also have numerous mechanisms to allow (or actively encourage) certain larger molecules to pass through.
Figure 14. Interpreting Michaelis-Menten saturation kinetics. William W. Cohen 27 Enzymes with more complicated struc- A molecule that is composed tures can lead to more complicated velo- of two identical subunits is a city-concentration curves, as shown in dimer; three identical subunits compose a trimer; Figure 15. A typical example would be and N identical subunits an enzyme with two parts, each of which compose a polymer. An has an active site (a location at which enzyme in which binding sites the substrate S can bind), and each of do not behave independently which has two possible conformations is an allosteric enzyme; in the example here, the or shapes.
A Computer Scientist's Guide to Cell Biology: A travelogue from a stranger in a strange land by William W. Cohen